LOEWE Center for
Insect Biotechnology
& Bioresources

Sören Schuler

Dr. rer. nat.

Scientist (Chemistry Group, FENPEC ID)

Phone: +49 641 99-37784

Email: soeren.schuler@ime.fraunhofer.de

Room: 701

Building: HBR58


Since 10/2018

Evotec International GmbH

Responsible for supervision and organization of the chemistry group at the ‘Fraunhofer Evotec Natural Product Excellence Center for Infectious Diseases’ (FENPEC ID)
07/2014–09/2018 Research fellow at the Sanofi-Fraunhofer Natural Product Center of Excellence (Frankfurt)
10/2010–11/2016 Doctoral thesis at the Institute of Organic Chemistry of the Justus-Liebig University Giessen
Supervisor: Prof. Dr. Peter R. Schreiner
02/2010–08/2010 Diploma thesis at the Institute of Organic Chemistry at the Karlsruher Institute of Technology (KIT)
Supervisor: Prof. Dr. Stefan Bräse and Dr. Moritz Biskup
10/2005–01/2010 Studies in chemistry at the University of Karlsruhe (TH)

Research Interests

  • Natural product chemistry
  • Dereplication, isolation, and structure elucidation
  • (Semi)total synthesis of natural products as well as organic chemistry in general
  • Medical chemistry


Jürjens G, Schuler SMM, Kurz M, Petit S, Couturier C, Jeannot F, Nguyen F, Wende RC, Hammann PE, Wilson DN, Bacqué E, Pöverlein C, Bauer A (2018) Total Synthesis and Structural Revision of the Antibiotic Tetrapeptide GE81112A Angewandte Chemie International Edition, 57 (37) , 12157-12161.
Niedek D, Schuler SMM, Eschmann C, Wende RC, Seitz A, Keul F, Schreiner PR (2017) Synthesis of Enantioenriched Phthalide and Isoindolinone Derivatives from 2-Formylbenzoic Acid. Synthesis, 49 (2) , 371-382.
Wende RC, Seitz A, Niedek D, Schuler SMM, Hofmann C, Becker J, Schreiner PR (2016) The Enantioselective Dakin–West Reaction. Angewandte Chemie International Edition, 55 (8) , 2719–2723.
Alachraf MW, Wende RC, Schuler SMM, Schreiner PR, Schrader W (2015) Functionality, Effectiveness, and Mechanistic Evaluation of a Multicatalyst-Promoted Reaction Sequence by Electrospray Ionization Mass Spectrometry. Chemistry – A European Journal, 21 (45) , 16203–16208.
Hofmann C, Schuler SMM, Wende RC, Schreiner PR (2014) En route to multicatalysis: kinetic resolution of trans-cycloalkane-1,2-diols via oxidative esterification Chemical Communications , 50 , 1221–1223.
Müller CE, Zell D, Hrdina R, Wende RC, Wanka L, Schuler SMM, Schreiner PR (2013) Lipophilic Oligopeptides for Chemo- and Enantioselective Acyl Transfer Reactions onto Alcohols The Journal of Organic Chemistry, 78 (17) , 8465–8484.