LOEWE Center for
Insect Biotechnology
& Bioresources

Marc F. Schetelig

Prof. Dr.

Group leader

Phone: +49 641 99-39504

Email: marc.schetelig@agrar.uni-giessen.de / marc.schetelig@ime.fraunhofer.de

Room: 1.30

Building: TIG

Vita

since 2016 Professor for Insect Biotechnology in Plant Protection
since 2014 Head of Insect Pest and Vector Control
since 2013 Fraunhofer Attract Group leader at the Fraunhofer Institute for Molecular Biology and Applied Ecology (IME), Gießen, Germany
since 2013 Emmy Noether Group leader at the Justus-Liebig-University Gießen, Germany
2008–2013 Research Molecular Geneticist at the USDA-ARS, USA
2004–2008 PhD at the Göttingen Centre for Molecular Biosciences (GZMB), Georg-August-University Göttingen, Germany
1999–2004 Diploma in Biochemistry at the University Bayreuth, Germany

Awards and Grants

  • 2014 - LOEWE Center for Insect Biotechnology & Bioresources (ZIB), Head: Prof. Dr. Andreas Vilcinskas
  • 2013 - Fraunhofer Attract Fellow, Fraunhofer Gesellschaft, Germany
  • 2012 - Emmy-Noether Fellowship from the German Research Foundation, Germany
  • 2010 - On-the-Spot award, ARS-CMAVE, USA
  • 2008 - United States Department of Agriculture (USDA-ARS) postdoctoral associate fellowship, USA
  • 2006 - DAAD VIGONI 2007/08 exchange program, Italy/Germany

Professional Societies and Engagement

  • 2016: World Health Organization (WHO)
  • 2016: Food and Agricultural Organization (FAO)
  • 2013 – present: German Research Foundation (DFG)
  • 2012 – present: International Atomic Energy Agency (IAEA)
  • 2009 – present: American Association for the Advancement of Science (AAAS)
  • 2009 – 2013: National Postdoc Association (NPA)
  • 2008 – 2013: United States Department of Agriculture (USDA)

Teaching

  • MP 025 – Biologische Schädlingsbekämpfung
  • MP 090 – Insect Biotechnology
  • BP 038 – Agrarökologie und integrierter Pflanzenschutz

Patent

Patent Application on Insect Population Control:  http://www.wipo.int/pctdb/en/wo.jsp?WO=2009115569

Media

IGTRCN - Insect Genetic Technologies Research Coordiantion Network

IAEA - New approaches for the sterilization of disease-carrying mosquitoes

Research Interests

General research interests are developmental biology, the development of pest control systems and the evaluation and comparison of transgenic systems for improving integrated pest management programs.

Prof. Schetelig is leading two research groups in Gießen, Germany:

The Emmy Noether Group awarded by the German Research Foundation to work on the risk assessment of transgenic insects at the Justus-Liebig University Gießen.

The Fraunhofer Attract Group to develop new pest control technologies for highly invasive fruit flies like Drosophila suzukii, the Spotted Wing Drosophila (SWD), at the Fraunhofer Institute for Molecular Biology and Applied Ecology (IME).

Current group members are:

Publications

Häcker I, Harrell II RA, Eichner G, Pilitt KL, O’Brochta DA, Handler AM, Schetelig MF (2017) Cre/lox-Recombinase-Mediated Cassette Exchange for Reversible Site-Specific Genomic Targeting of the Disease Vector, Aedes aegypti Scientific Reports, 7: 43883
Genç H, Schetelig MF, Nirmala X, Handler AM (2016) Germline transformation of the olive fruit fly, (Rossi) (Diptera: Tephritidae) with a piggyBac transposon vector Turkish Journal of Biology, 40 , 845-855.
Papanicolaou A, Schetelig MF, Arensburger P, Atkinson PW, Benoit JB, Bourtzis K, Castañera P, Cavanaugh JP, Chao H, Childers C, Curril I, Dinh H, Doddapaneni H, Dolan A, Dugan S, Friedrich M, Gasperi G, Geib S, Georgakilas G, Gibbs RA, Giers SD, Gomulski LM, González-Guzmán M, Guillem-Amat A, Han Y, Hatzigeorgiou AG, Hernández-Crespo P, Hughes DS, Jones JW, Karagkouni D, Koskinioti P, Lee SL, Malacrida AR, Manni M, Mathiopoulos K, Meccariello A, Murali SC, Murphy TD, Muzny DM, Oberhofer G, Ortego F, Paraskevopoulou MD, Poelchau M, Qu J, Reczko M, Robertson HM, Rosendale AJ, Rosselot AE, Saccone G, Salvemini M, Savini G, Schreiner P, Scolari F, Siciliano P, Sim SB, Tsiamis G, Ureña E, Vlachos IS, Werren JH, Wimmer EA, Worley KC, Zacharopoulou A, Richards S, Handler AM (2016) The whole genome sequence of the Mediterranean fruit fly, Ceratitis capitata (Wiedemann), reveals insights into the biology and adaptive evolution of a highly invasive pest species. Genome Biology, 17 (1) , 1-17.
Schetelig MF, Targovska A, Meza JS, Bourtzis K, Handler AM (2016) Tetracycline-suppressible female lethality and sterility in the Mexican fruit fly, Anastrepha ludens. Insect Molecular Biology, 25 (4) , 500-508.
Schwirz J, Fischbach M, Vilcinskas A, Fischer R, Schetelig MF (2016) Monitoring data and future control possibilities for Drosophila suzukii in Germany. In: Proceedings of the 9th Int Symposium on Fruit Flies of Economic Importance, , 310-322.
Nirmala X, Schetelig MF, Zimowska GJ, Zhou L, Handler AM (2015) Pro-apoptotic gene regulation and its activation by gamma-irradiation in the Caribbean fruit fly, Anastrepha suspensa. Apoptosis, 20 (1) , 1–9.
Gilles J, Schetelig MF, Scolari F, Marec F, Capurro ML, Franz G, Bourtzis K (2014) Towards mosquito sterile insect technique programmes: Exploring genetic, molecular, mechanical and behavioural methods of sex separation in mosquitoes. Acta Tropica, 132S , S178–S187.
Handler AM, Schetelig MF (2014) Tephritid Fruit Fly Transgenesis and Applications. , in Transgenic Insects: Techniques and Applications, Benedict, MQ (Eds.) , 117–137. CABI : Wallingford
Hokanson KE, Dawson WO, Handler AM, Schetelig MF, St Leger RJ (2014) Not all GMOs are crop plants: non-plant GMO applications in agriculture. Transgenic Research, 23 (6) , 1057–1068.
Meza JS, Díaz-Fleischer F, Sánchez-Velásquez LR, Zepeda-Cisneros CS, Handler AM, Schetelig MF (2014) Fitness cost implications of phiC31-mediated site-specific integrations in target-site strains of the Mexican fruit fly, Anastrepha ludens (Diptera: Tephritidae) PLoS One, 9 (10) e109690 , 1–10.
Meza JS, Schetelig MF, Zepeda-Cisneros CS, Handler AM (2014) Male-specific Y-linked transgene markers to enhance biologically-based control of the Mexican fruit fly, Anastrepha ludens (Diptera: Tephritidae) BMC Genetics, 15 Suppl 2:S4 , 1-7.
Nirmala X, Schetelig MF, Zimowska GJ, Zhou L, Handler AM (2014) Pro-apoptotic gene regulation and its activation by gamma-irradiation in the Caribbean fruit fly, Anastrepha suspense Apoptosis, 20 (1) , 1–9.
Scolari F, Yuval B, Gomulski LM, Schetelig MF, Gabrieli P, Bassetti F, Wimmer EA, Malacrida AR, Gasperi G (2014) Polyandry in the medfly – shifts in paternity mediated by sperm stratification and mixing. BMC Genetics, 15 Suppl 2:S10 , 1–8.
Nirmala X, Schetelig MF, Yu F, Handler AM (2013) An EST database of the Caribbean fruit fly, Anastrepha suspensa (Diptera: Tephritidae) Gene, 517 (2) , 212-217.
Ogaugwu CE, Schetelig MF, Wimmer EA (2013) Transgenic sexing system for Ceratitis capitata (Diptera: Tephritidae) based on female-specific embryonic lethality Insect Biochemistry and Molecular Biology , 43 (1) , 1-8.
Schetelig MF, Handler AM (2013) Germline transformation of the spotted wing drosophilid, Drosophila suzukii, with a piggyBac transposon vector. Genetica, 141 (4-6) , 189−193.
Schetelig MF, Handler AM (2013) Y-linked markers for improved population control of the tephritid fruit fly pest, Anastrepha suspensa. Advances in Biochemical Engineering/Biotechnology, 136 , 123-133.
Schetelig MF, Handler AM (2013) A functional comparison of the 3xP3 Promoter by recombinase-mediated cassette exchange in Drosophila and a Tephritid Fly, Anastrepha suspensa G3: Genes, Genomes, Genetics, 3 (4) , 687–693.
Schetelig MF, Handler AM (2012) Strategy for enhanced transgenic strain development for embryonic conditional lethality in Anastrepha suspensa PNAS, 24 , 9348-9353.
Schetelig MF, Handler AM (2012) A transgenic embryonic sexing system for Anastrepha suspensa (Diptera: Tephritidae) Insect Biochemistry and Molecular Biology , 42 , 790-795.
Schetelig MF, Milano A, Saccone G, Handler AM (2012) Male only progeny in Anastrepha suspensa by RNAi-induced sex reversion of chromosomal females Insect Biochemistry and Molecular Biology , 42 , 51-57.
Schetelig MF, Nirmala X, Handler AM (2011) Pro-apoptotic cell death genes, hid and reaper, from the tephritid pest species, Anastrepha suspensa Apoptosis, 16 , 759-768.
Schetelig MF, Ogaugwu CE, Wimmer EA (2011) Development of a transgenic sexing system based on female-specific embryonic lethality in Ceratitis capitata (Diptera: Tephritidae) , in Proceedings 8th International Symposium on Fruit Flies of Economic Importance, , 106-118. Valencia, Spain, 2010
Schetelig MF, Wimmer EA (2011) Insect Transgenesis and the Sterile Insect Technique , in In Insect Biotechnology , Vilcinskas A (Eds.) , 169-194.
Schetelig MF, Götschel F, Viktorinová I, Handler AM, Wimmer EA (2010) Recombination technologies for enhanced transgene stability in bioengineered insects for the Sterile Insect Technique Genetica, 139 , 71-78.
Schetelig MF, Caceres C, Zacharopoulou A, Franz G, Wimmer EA (2009) Conditional embryonic lethality to improve the sterile insect technique in Ceratitis capitata (Diptera: Tephritidae) BMC Biology, 7 (4) , 1-13.
Schetelig MF, Scolari F, Handler AM, Kittelmann S, Gasperi G, Wimmer EA (2009) Site-specific recombination for the modification of transgenic strains of the Mediterranean fruit fly Ceratitis capitata PNAS, 106 (43) , 18171-18176.
Schetelig MF, Schmid BGM, Zimowska G, Wimmer EA (2008) Plasticity in mRNA expression and localization of orthodenticle within higher Diptera Plasticity in mRNA expression and localization of orthodenticle within higher Diptera, 10 (6) , 700-704.
Schetelig MF, Scolari F, Handler AM, Gasperi G, Wimmer EA (2008) New genetic tools for improving SIT in Ceratitis capitata: embryonic lethality and sperm marking. , in New genetic tools for improving SIT in Ceratitis capitata: embryonic lethality and sperm marking., Malavasi A (Eds.) Salvador, Bahia, Brazil
Scolari F, Schetelig MF, Bertin S, Malacrida AR, Gasperi G, Wimmer EA (2008) Fluorescent Sperm Marking to Improve the Fight against the Pest Insect Ceratitis capitata (Wiedemann; Diptera: Tephritidae) New Biotechnology, 25 (1) , 76-84.
Scolari F, Schetelig MF, Gabrieli P, Siciliano P, Gomulski LM, Karam N, Wimmer EA, Malacrida AR, Gasperi G (2008) Insect transgenesis applied to tephritid pest control Journal of Applied Entomology, 132 (9-10) , 820-831.
Schetelig MF, Horn C, Handler AM, Wimmer EA (2007) Development of an embryonic lethality system for transgenic SIT in the fruit pest Ceratitis capitata , in Area-Wide Control of Insect Pests: From Research to Field Implementation , Vreysen, MJB, Robinson AS, Hendrichs, J (Eds.) , 85-93.

LOEWE Center for
Insect Biotechnology
& Bioresources
© 2014