Phone: +49 641 99-37786
|05/2018||Change of name (Mitsotakis to Gegner)|
|since 07/2014||PhD Student Fraunhofer Institute for Molecular Biology and Applied Ecology IME
Bioresources Project Group
|10/2011–04/2014||M. Sc. student in Biochemistry and Molecular Biology at University of Bayreuth
Master thesis: 'Epigenetic DNA-Modification Analysis of salt-stressed fungi'
|10/2008–9/2011||B. Sc. student in Biochemistry at University of Bayreuth
Bachelor thesis: 'Modulation der humanen Sirtuin-Isoformen 3 und 5 durch Kleinmoleküle'
Epigenetics is the study of stable and often hereditary changes e.g. of the phenotype, which are not mediated by DNA sequence. One epigenetic modification is the DNA methylation of cytosines, which is the most common form of DNA modification in eukaryotes. It plays an important role in the adaption of organisms to changes in their environment. In my PhD thesis I investigate the DNA-methylation of insects species in relation to different conditions like for example bacterial infections in the model organism Manduca sexta. I also want to get a deeper understanding on how DNA-methylation interacts with other epigenetic signals. Furthermore, I am especially interested in how DNA-methylation influences gene regulation and consequently protein expression or metabolite production.