LOEWE Center for
Insect Biotechnology
& Bioresources

Jasmin Gegner

MSc

PhD Student

Phone: +49 641 99-37786

Email: jasmin.gegner@ime.fraunhofer.de

Room: B772

Building: HBR58

Vita

05/2018 Change of name (Mitsotakis to Gegner)
since 07/2014 PhD Student Fraunhofer Institute for Molecular Biology and Applied Ecology IME
Bioresources Project Group
10/2011–04/2014 M. Sc. student in Biochemistry and Molecular Biology at University of Bayreuth
Master thesis: 'Epigenetic DNA-Modification Analysis of salt-stressed fungi'
10/2008–9/2011 B. Sc. student in Biochemistry at University of Bayreuth
Bachelor thesis: 'Modulation der humanen Sirtuin-Isoformen 3 und 5 durch Kleinmoleküle'

Research Interests

Epigenetics is the study of stable and often hereditary changes e.g. of the phenotype, which are not mediated by DNA sequence. One epigenetic modification is the DNA methylation of cytosines, which is the most common form of DNA modification in eukaryotes. It plays an important role in the adaption of organisms to changes in their environment. In my PhD thesis I investigate the DNA-methylation of insects species in relation to different conditions like for example bacterial infections in the model organism Manduca sexta. I also want to get a deeper understanding on how DNA-methylation interacts with other epigenetic signals. Furthermore, I am especially interested in how DNA-methylation influences gene regulation and consequently protein expression or metabolite production.